重组人血小板源性生长因子-AB(Human PDGF-AB)

重组人血小板源性生长因子-AB(Human PDGF-AB)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 2μg/10μg/1mg
货号: CYT-342
CAS号:
上海希美化学有限公司
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PDGF AB Human
Platelet-Derived Growth Factor AB Human Recombinant
Catalog No. CYT-342

Synonyms:
Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AB.

Introduction:
The term ‘PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets.They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix.

Description:
Platelet-Derived Growth Factor AB Human Recombinant is a heterodimeric, non-glycosylated, polypeptide chain containing 234 amino acids consisting of 13.3kDa alpha-chain and 12.2 beta-chain having a total molecular mass of 25.5kDa.
PDGF-AB is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The protein was lyophilized with no additives.

Solubility:
It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AB in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized Platelet-derived Growth Factor AB although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution PDGF-AB should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino acid sequence:
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ser-Ile-Glu-Glu-alpha chain and Met-Ser-Leu-Gly-Ser-beta chain.

Biological Activity:
The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T3 indicator cells (measured by 3H-thymidine uptake) is < 1 ng/ml, corresponding to a Specific Activity of 1 MIU/mg.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» PDGF A Human
» PDGF AA Human
» PDGF AA Human, Yeast
» PDGF AA Mouse
» PDGF B Human
» PDGF BB Human
» PDGF BB Human, Yeast
» PDGF BB Mouse

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重组人血小板源性生长因子-AB(Human PDGF-AB)由上海希美化学有限公司为您提供,货号CYT-342,规格:2μg/10μg/1mg,CAS号:,如您想了解更多关于重组人血小板源性生长因子-AB(Human PDGF-AB)价格、重组人血小板源性生长因子-AB(Human PDGF-AB)结构式、批发、用途等信息,欢迎咨询。除供应重组人血小板源性生长因子-AB(Human PDGF-AB)外,还可为您提供大鼠血小板衍生生长因子AB(PDGF-AB)ELISA Kit、重组人血小板源性生长因子-AA(Human PDGF-AA)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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