Recombinant Human Trefoil Factor-1(Human TFF1)

Recombinant Human Trefoil Factor-1(Human TFF1)

参考价：面议
供货周期： 一周
品牌： Prospect Biosystems
规格： 5μg/20μg/1mg
货号： CYT-586
CAS号：
上海希美化学有限公司
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TFF1 Human
Trefoil Factor-1 Human Recombinant
Catalog No. CYT-586

Synonyms:
TFF-1, TFF1, pS2, BCEI, HPS, HP1.A, pNR-2, D21S21, pS2 protein, Trefoil factor 1, Breast cancer estrogen-inducible protein.

Introduction:
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are stable secretory proteins expressed in the gastrointestinal tract (gastric mucosa), and are involved in intestinal mucosal defense and repair. TFF1 is an essential protein for normal differentiation of the antral and pyloric gastric mucosa and functions as a gastric-specific tumor suppressor gene. TFF1 is a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 protects the mucosa from isults, stabilizes the mucus layer, & affects healing of the epithelium. TFF1 is commonly expressed in tumors. TFF1 is related with the cell membrane of MCF-7 cells. High levels of TFF1 and TFF2 are found in serum from inflammatory bowel disease.

Description:
TFF-1 Human Recombinant produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 2 x 60 amino acids which includes a 40 amino acid trefoil motif containing 3 conserved interamolecular disulfide bonds and having a total molecular mass of 13.2 kDa.
TFF-1 Human Recombinant is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The protein was lyophilized after dialysis against 1xPBS pH-7.4.

Solubility:
It is recommended to reconstitute the lyophilized TFF1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stability:
Lyophilized TFF1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TFF1 should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity:
Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.


Amino acid sequence:
EAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFY
PNTIDVPPEEECEF

Biological Activity:
Determined by its ability to activate ERK1/2 (a MAPkinase signaling molecule) using a concentration 1.0-2.0 μg/ml.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» TFF1 Human, His
» TFF2 Human
» TFF2 Human, His
» TFF3 Human

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Recombinant Human Trefoil Factor-1(Human TFF1)由上海希美化学有限公司为您提供，货号CYT-586，规格：5μg/20μg/1mg，CAS号：，如您想了解更多关于Recombinant Human Trefoil Factor-1(Human TFF1)价格、Recombinant Human Trefoil Factor-1(Human TFF1)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Trefoil Factor-1(Human TFF1)外，还可为您提供Recombinant E.Coli Transcription Termination/Antitermination L Factor(NusA)、大鼠尿液三叶因子3(TFF-3)ELISA kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。
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