| 供货周期： | 一周 |
| 品牌： | Prospect Biosystems |
| 规格： | 5mg/25mg/100mg |
| 货号： | HOR-260 |
| CAS号： |
Leuprorelin Human
Leuprolide Human
Catalog No. HOR-260
Synonyms:
Leuprolide, Leuprorelin.
Introduction:
Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist).
By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH).
Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF.
Description:
Leuprolide Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
The Leuprorelin was lyophilized from a concentrated (1 mg/ml) solution with no additives.
Solubility:
It is recommended to reconstitute the lyophilized Leoprolide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability:
Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Leuprorelin should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 98.0% as determined by RP-HPLC.
Amino acid sequence:
Glu-His-Trp-Ser-Tyr-DLeu-Leu-Arg-Pro-NHEt.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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