重组人鸟苷酸环化酶激活剂2B(Human GUCA2B)|2μg/10μg/1mg|HOR-245-上海希美化学有限公司

产品详情

GUCA2B Human
Prouroguanylin Human Recombinant
Catalog No. HOR-245

Synonyms:
Guanylate cyclase activator 2B, UGN, GCAP-II, GUCA2B.

Introduction:
Prouroguanylin is a 112-amino-acid prohormone precursor of uroguanylin- mature biologically active 16-amino-acid peptide cleaved from its C-terminus. Guanylin binds to receptor-guanylate cyclases (CG-C) resulting in increased intracellular cGMP levels leading to CFTCR (Cystic Fibrosis Transmembrane Conductance Regulator) activation and subsequent rise in fluid and electrolyte secretion into the lumen.
Prouroguanyline knock-out mice showed impaired renal excretion of external NaCl leading to elevated blood pressure independent of the level of diatary salt intake.
Prouroguanylin is the predominant circulating molecular form found in circulation and in biological fluids.

Description:
Prouroguanylin Human Recombinant is 10 kDa protein containing 88 amino acid residues of the human prouroguanylin and 2 additional amino acid residues.
GPVYIQYQGF RVQLESMKKL SDLEAQWAPS PRLQAQSLLP AVCHHPALPQ DLQPVCASQE ASSIFKTLRT IANDDCELCV NVACTGCL
The Prouroguanylin is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
Sterile filtered and lyophilized from 0.5 mg/ml in 50mM Phosphate buffer pH-7.4.

Specificity:
The recombinant sequence is 100% homologous to the native human sequence.

Purification Method:
Three-step procedure using IMAC and size exclusion chromatography before and after refolding.

Solubility:
Add 0.2 ml of deionized H2O and let the lyophilized pellet dissolve completely.

Stability:
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated thaw-freeze cycles and store at
-80°C. Reconstituted protein can be stored at 4°C for a limited period of time.
The lyophilized protein remains stable until the expiry date when stored at -20°C.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Applications:
Western blotting, ELISA

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

重组人鸟苷酸环化酶激活剂2B(Human GUCA2B)由上海希美化学有限公司为您提供，货号HOR-245，规格：2μg/10μg/1mg，CAS号：，如您想了解更多关于重组人鸟苷酸环化酶激活剂2B(Human GUCA2B)价格、重组人鸟苷酸环化酶激活剂2B(Human GUCA2B)结构式、批发、用途等信息，欢迎咨询。除供应重组人鸟苷酸环化酶激活剂2B(Human GUCA2B)外，还可为您提供猪组织型纤溶酶原激活剂(t-PA)ELISA Kit、兔子组织型纤溶酶原激活剂(t-PA)ELISA Kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：	Prospect Biosystems
规格：	2μg/10μg/1mg
货号：	HOR-245
CAS号：