| 供货周期： | 一周 |
| 品牌： | Prospect Biosystems |
| 规格： | 50μg/200μg/1mg |
| 货号： | ENZ-349 |
| CAS号： |
APC Human
Activated Protein C Human Recombinant
Catalog No. ENZ-349
Synonyms:
Coagulation factor V, Activated protein C cofactor, FVL, PCCF, factor V, APC.
Introduction:
Activated Protein C exerts an antithrombotic effect by inhibiting Factors Va and VIIIa.
In vitro data indicate that Activated Protein C has indirect profibrinolytic activity through its ability to inhibit plasminogen activator inhibitor-1 (PAI-1) and limiting generation of activated thrombin-activatable-fibrinolysis-inhibitor. Additionally, in vitro data indicate that Activated Protein C may exert an anti-inflammatory effect by inhibiting human tumor necrosis factor production by monocytes, by blocking leukocyte adhesion to selectins, and by limiting the thrombin-induced inflammatory responses within the microvascular endothelium.
Description:
Activated Protein C Human Recombinant produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain having a molecular mass of 55kDa.
Activated Protein C Human Recombinant is a serine protease with the same amino acid sequence and glycosilation sites as the human plasma-derived Activated Protein C.
The APC is purified by proprietary chromatographic techniques.
Source:
Chinese Hamster Ovary Cells (CHO).
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
Each mg protein contains 7. 6mg sodium chloride, 1.5 mg citrate and 6 mg sucrose.
Solubility:
It is recommended to reconstitute the lyophilized Coagulation factor V in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Stability:
Lyophilized Factor V although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution APC should be stored at 4°C between 2-7 days and for future use below
-18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 99.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE..
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
相关产品
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
3-D Life Dextran-PEG Hydrogel Kit
3-D Life Dextran-CD Hydrogel Kit（3D 细胞培养 葡聚糖马来酰亚胺-聚乙二醇仿生水凝胶试剂盒）
3-D水凝胶PEG-Link（聚乙二醇交联剂）（3D细胞培养 PEG 交联物（非降解））
3-D Life CD-Link（3D细胞培养 CD 交联物（可细胞降解））
3-D Life Maleimide-Dextran Set（3D 细胞培养葡聚糖马来酰亚胺聚合物）
3D 细胞培养RGD多肽（粘附剂）3-D Life RGD Peptide
3-D Life Scrambled RGD Peptide
Pig C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Mouse C-type lectin domain family 5 member A(CLEC5A)ELISA kit
Human C-type lectin domain family 5 member A(CLEC5A)ELISA kit
无形体IgM免疫荧光试剂盒
牛甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
鸡甘油醛-3-磷酸脱氢酶(GAPDH)ELISA kit
工商信息
信息已认证
联系方式
详细地址
关注
拨打电话
留言咨询
