Recombinant Human Beta-Site APP-Cleaving Enzyme 1(BACE1)|1μg/5μg/50μg|ENZ-358-上海希美化学有限公司

产品详情

BACE1 Human
Beta-Site APP-Cleaving Enzyme 1 Human Recombinant
Catalog No. ENZ-358

Synonyms:
ASP2, BACE, HSPC104, Memapsin-2, Aspartyl protease 2, Asp 2, BACE1, Beta-secretase 1, EC 3.4.23.46, Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, FLJ90568, KIAA1149.

Introduction:
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. BACE1 is a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
BACE1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE-1 cleaves at the n-terminus of the a-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated c-terminal fragment which is later released by gamma-secretase

Description:
BACE-1 Human Recombinant is expressed in E. coli containing 366 amino acids 28-393.
The BACE1 is purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
20mM Tris, 20mM KCl, 0.3M NaCl and 10% glycerol, pH 7.8.

Stability:
Store at 4°C if entire vial will be used within 1-2 weeks.
Store, frozen at -20°C for longer periods of time.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95% as determined by SDS-PAGE.

Applications:
Recombinant BACE-1 is an excellent protein for proteases functional assays; highly active, excellent for BACE-1 inhibitor screen assay.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Recombinant Human Beta-Site APP-Cleaving Enzyme 1(BACE1)由上海希美化学有限公司为您提供，货号ENZ-358，规格：1μg/5μg/50μg，CAS号：，如您想了解更多关于Recombinant Human Beta-Site APP-Cleaving Enzyme 1(BACE1)价格、Recombinant Human Beta-Site APP-Cleaving Enzyme 1(BACE1)结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Beta-Site APP-Cleaving Enzyme 1(BACE1)外，还可为您提供大鼠β位淀粉样前体蛋白裂解酶2(BACE2)ELISA Kit、ACE(angiotensin converting enzyme)antibody等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

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企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：	Prospect Biosystems
规格：	1μg/5μg/50μg
货号：	ENZ-358
CAS号：