| 供货周期： | 一周 |
| 品牌： | Prospect Biosystems |
| 规格： | 5μg/25μg/1mg |
| 货号： | PKA-347 |
| CAS号： |
YWHAH Human
Tyr-3/Trp-5 Monooxygenase Activation Protein ETA Human Recombinant
Catalog No. PKA-347
Synonyms:
14-3-3 ETA, YWHAH, YWHA1, Protein AS1, Tyr-3/Trp-5 Monooxygenase Activation Protein ETA.
Introduction:
YWHAH belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. 14-3-3 ETA is found in plants and mammals, and there is 99% identity to the mouse, rat and bovine orthologs. YWHAH gene contains a 7 base pair repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
14-3-3 eta is specific to the site of joint inflammation.
14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, though there is no specific staining for the 14-3-3 eta subunit.
There are 3 different isoforms types of 14-3-3: Beta, Gamma and ETA that are DAL-1/Protein 4.1B-binding proteins.
Description:
YWHAH Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 266 amino acids and having a molecular mass of 30.3 kDa.
YWHAH is fused to N-Terminus His Tag and purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile filtered colorless solution.
Formulation:
YWHAH solution containing 20mM Tris pH-8.
Stability:
YWHAH Human Recombinant although stable at 4°C for 1 week, should be stored desiccated below -18°C.
Please prevent freeze thaw cycles.
Amino acid sequence:
MGSSHHHHHH SSGLVPRGSH MGDREQLLQR ARLAEQAERY DMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN
Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
» YWHAB Human
» YWHAE Human
» YWHAG Human
» YWHAG Human, His
» YWHAQ Human
» YWHAZ Human
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