重组人蛋白激酶C-α(Human PKC-a)|2μg/10μg/100μg|PKA-218-上海希美化学有限公司

产品详情

PKC-a Human
Protein Kinase C alpha Human Recombinant
Catalog No. PKA-218

Synonyms:
Protein kinase C alpha type, EC 2.7.11.13, PKC-alpha, PKC-A, PRKCA, AAG6, PKCA, PRKACA, MGC129900, MGC129901.

Introduction:
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Description:
Protein Kinase C alpha Human Recombinant produced in Sf9 is a glycosylated, polypeptide chain containing amino acids 2-672 and having a molecular mass of 80 KD. This protein is the full-length form of the protein with an amino terminal poly His-tag.
PKC-a is purified by proprietary chromatographic techniques.

Source:
Sf9 insect cells.

Formulation:
PKC-a is supplied at a of 0.3mg/ml in 50mM Tris, pH 7.4, 0.1M NaCl, 20% glycerol, 1mM DTT, 0.1mM EDTA, 0.2mM PMSF and 0.03% Brij-35.

Unit Definition:
7200- 9000 units/mg. One unit of PKC-a activity transfers 1 nmole of phosphate to a PKC substrate peptide (myelin basic protein 4-14) per minute at 30°C.
Recombinant human active PKC-a also phosphorylates full length myelin basic protein, histone, MARKS, and GSK-3b. Activity requires incubation with lipid activators, and may vary depending on the substrate and reaction conditions.

Storage Conditions:
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.

Purity:
Greater than 95% as determined by SDS-PAGE.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» PKC-b I Human
» PKC-b II Human
» PKC-d Human
» PKC-g Human
» PKC-t Human
» PRKCE Human

重组人蛋白激酶C-α(Human PKC-a)由上海希美化学有限公司为您提供，货号PKA-218，规格：2μg/10μg/100μg，CAS号：，如您想了解更多关于重组人蛋白激酶C-α(Human PKC-a)价格、重组人蛋白激酶C-α(Human PKC-a)结构式、批发、用途等信息，欢迎咨询。除供应重组人蛋白激酶C-α(Human PKC-a)外，还可为您提供小鼠磷酸化蛋白激酶C(P-PKC)ELISA Kit、山羊超氧化物歧化酶1,可溶性(SOD1)ELISA Kit 等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海希美化学客户服务电话，售前、售后均可联系。

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】

供货周期：	一周
品牌：	Prospect Biosystems
规格：	2μg/10μg/100μg
货号：	PKA-218
CAS号：