重组人肌酸激酶同工酶MM-1(Human CKMM Type-1)

重组人肌酸激酶同工酶MM-1(Human CKMM Type-1)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 10μg/50μg/1mg
货号: CKI-271
CAS号:
上海希美化学有限公司
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CKMMITI Human
Creatine Kinase MM Isoenzyme Type-I Human Recombinant
Catalog No. CKI-271

Synonyms:
Creatine kinase M-type, EC 2.7.3.2, Creatine kinase M chain, M-CK, CKM, CKMM, CKMMITI.

Introduction:
Creatine Kinase MM is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Description:
CKMMITI Human Recombinant without C-terminal Lysine on both chains produced in Pichia Pastoris is a glycosylated polypeptide chain having an identical amino acid sequence compared to the native enzyme, purified under non-denaturing conditions and reacts with polyclonal antibodies to MM Isoenzyme in ELISA.
The CKMMITI is purified by proprietary chromatographic techniques.

Source:
Pichia Pastoris.

Physical Appearance:
Sterile Filtered colourless liquid formulation.

Formulation:
The protein (7.14 mg/ml) contains 0.1M Tris-HCl, 0.075M NaCl, 10mM 2-ME, 50% glycerol, 0.1% sodium azide, pH 7.2.

Stability:
CKMMITI although stable at 15°C for 7 days, should be stored desiccated below -18°C.
Please prevent freeze-thaw cycles.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Biological Activity:
The biological activity measured by the enzymatic activity of Creatine phosphokinase procedure No.45-UV, 1IU-1 µmole creatine phosphate was 500IU/mg at 37 degrees celsius.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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