供货周期: | 一周 |
品牌: | Prospect Biosystems |
规格: | 1mg/20mg/100mg |
货号: | PRO-414 |
CAS号: |
Aprotinin Bovine
Aprotinin Bovine Recombinant
Catalog No. PRO-414
Synonyms:
Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP.
Introduction:
Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
Description:
Aprotinin Bovine Recombinant is approximately 6,512 Dalton highly purified and designed specifically for cell culture applications, protein purification, diagnostic testing and pharmaceuticals.
It is produced without the use of animal- or human-derived materials and is therefore free from risk of contaminating human or animal-derived viruses or prions.
Source:
Maize (Corn)
Physical Appearance:
Sterile Filtered lyophilized powder.
Formulation:
The protein was lyophilized without any additives.
Solubility:
It is recommended to reconstitute the Aprotinin in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability:
Aprotinin although stable at room temperature for 3 weeks, should be stored at 4°C.
Purity:
Greater than 90.0% as determind by Gel Electrophoresis.
Activity:
4.6 TIU/mg
Unit Defenition:
One Trypsin Inhibitory Unit (TIU) is equal to the amount of inhibitor with the ability to inhibit two trypsin units by 50% where one trypsin unit will hydrolyze 1.0 mmole of N-alpha-benzoyl-DL-Arginine-p-Nitroanilide (BAPNA) per minute at pH 7.8 at 25°C.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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