重组人钙调磷酸酶1(Recombinant Human DSC1)

重组人钙调磷酸酶1(Recombinant Human DSC1)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 5μg/20μg/1mg
货号: PRO-319
CAS号:
上海希美化学有限公司
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RCAN1 Human
Regulator of Calcineurin 1 Human Recombinant
Catalog No. PRO-319

Synonyms:
Calcipressin-1, Regulator of calcineurin 1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Adapt78, RCAN1, ADAPT78, CSP1, DSC1, DSCR1, RCN1.

Introduction:
RCAN1 encoded by a gene located in the human chromosome 21, interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. RCAN1 is located in the minimal candidate region for the Down syndrome phenotype, and is over expressed in the brain of Down syndrome fetuses. Chronic over expression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development.

Description:
RCAN1 Isoform-b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids and having a molecular mass of 13 kDa.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered colorless solution.

Formulation:
The protein solution contains 20mM Tris-HCl pH-7.5, 100mM NaCl and 1mM DTT.

Stability:
RCAN1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Amino Acid Sequence:
MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGPGEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS.

Purity:
Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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重组人钙调磷酸酶1(Recombinant Human DSC1)由上海希美化学有限公司为您提供,货号PRO-319,规格:5μg/20μg/1mg,CAS号:,如您想了解更多关于重组人钙调磷酸酶1(Recombinant Human DSC1)价格、重组人钙调磷酸酶1(Recombinant Human DSC1)结构式、批发、用途等信息,欢迎咨询。除供应重组人钙调磷酸酶1(Recombinant Human DSC1)外,还可为您提供人钙调磷酸酶(CaN)ELISA Kit、猕猴骨特异性碱性磷酸酶B(ALP-B)ELISA Kit等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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