Human Factor VIII|400IU/800IU/1200IU|PRO-317-上海希美化学有限公司

Human Factor VIII

参考价：面议

供货周期：

一周

品牌：

Prospect Biosystems

规格：

400IU/800IU/1200IU

货号：

PRO-317

CAS号：

产品详情

Factor-VIII Human
Factor VIII Human
Catalog No. PRO-317

Synonyms:
Coagulation factor VIII, Procoagulant component, Antihemophilic factor, AHF, F8, F8C, F8B, HEMA, FVIII, DXS1253E, F8 protein.

Introduction:
Coagulation factor VIII participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Description:
Human Facor VIII produced from Human Plasma is effective in the correction and prevention of severe bleeding episodes attributed to Factor VIII deficiency.
The Factor-VIII is purified by proprietary chromatographic techniques.

Source:
Human Plasma

Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation:
The lyophilized protein 200IU/ml was lyophilized from a sterile solution containing 1.5% Glycine, 160mM Calcium chloride and 25mM NaCitrate and 25mM NaCl.

Solubility:
It is recommended to reconstitute the lyophilized Factor-VIII in sterile 18MΩ-cm H2O at a concentration of 200IU/ml, which can then be further diluted to other aqueous solutions.
Make sure that the vial has reached room temperature prior to its reconstitution, otherwise it might precipitate.

Stability:
Lyophilized Factor-VIII although stable at room temperature for 1 week, should be stored desiccated between 2-8°C. Upon reconstitution Factor-VIII should be storedat 4°C.

Biological Activity:
The potency per mg was tested and found to be 150 Units/mg.

Human Virus Test:
The plasma is collected from donors with Hepatitis B vaccinated.
Each unit of plasma has been tested for HBsAg, Anti-HIV-1/2 plus O and Anti-HCV by using the imported kits which are approved by Federal Drug Administration (FDA).

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» Factor IX Human
» Factor VIIa Human
» Factor VIII RA Human
» Factor-IX Antibody
» Factor-VIII Human Recombinant

Business information

工商信息

信息已认证

企业名称: 上海希美化学有限公司
企业类型:
信用代码: 310228001203103
成立日期: 2009年05月31日
注册资本: 10
经营范围: 化工原料及产品(除危险化学品、监控化学品、烟花爆竹、民用爆炸物品、易制毒化学品),实验室设备,仪器仪表,金属制品,电子产品,机电产品销售,从事化工科技、计算机科技领域内技术开发、技术咨询、技术服务。【依法须经批准的项目,经相关部门批准后方可开展经营活动】