Recombinant Human IRF4/MUM-1

Recombinant Human IRF4/MUM-1

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 2μg/5μg/10μg
货号: PRO-513
CAS号:
上海希美化学有限公司
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IRF4 Human
IRF4 Human Recombinant
Catalog No. PRO-513

Synonyms:
Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, NF-EM5, Multiple myeloma oncogene 1, IRF4, MUM1.

Introduction:
IRF4 is a transcriptional activator, belonging to the IRF family. It binds to the interferon- stimulated response element (ISRE) of the MHC Class I promoter (but is not induced by Interferons). IRF4 binds the immunoglobulin lambda light chain enhancer, together with Pu.1. It most likely plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
IRF4 / MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B cells mainly located in the "light zone". Its morphologic spectrum ranged from that of centrocyte to that of a plasmablast/plasma cell, and it displayed a phenotype (MUM1+/Bcl-6/Ki67 ) different from that of most GC B cells (MUM1 /Bcl-6+/Ki67+) and mantle B cells (MUM1 /Bcl-6 /Ki67 ).

Description:
IRF4 Human Recombinant (aa 144-451) expressed in E.coli. IRF4 is antibody reactive. The IRF4 is fused to a GST tag and purified by proprietary chromatographic techniques.

Source:
Escherichia Coli.

Physical Appearance:
Sterile Filtered clear solution.

Formulation:
IRF-4 in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.

Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.

Applications:
• ELISA
• Inhibition Assays
• Western Blotting

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Recombinant Human IRF4/MUM-1由上海希美化学有限公司为您提供,货号PRO-513,规格:2μg/5μg/10μg,CAS号:,如您想了解更多关于Recombinant Human IRF4/MUM-1价格、Recombinant Human IRF4/MUM-1结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human IRF4/MUM-1外,还可为您提供重组人干扰素调节因子-3(Human IRF-3)、重组人波形蛋白(Recombinant Human Vimentin)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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