人类肌红蛋白(Human Myoglobin)

人类肌红蛋白(Human Myoglobin)

参考价:面议
供货周期: 一周
品牌: Prospect Biosystems
规格: 200μg/1mg/10mg
货号: PRO-565
CAS号:
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Myoglobin Human
Myoglobin Human
Catalog No. PRO-565

Synonyms:
Myoglobin, MB, PVALB, MGC13548.

Introduction:
Myoglobin is a member of the globin superfamily and can be found in skeletal and cardiac muscles. It is a haemoprotein that contributs to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. Myoglobin has a single-chain globular structure of 153 amino acids, containing a heme prosthetic group (iron-containing porphyrin) in the core around which the remaining apoprotein folds. Myoglobin has 8 alpha helices and a hydrophobic core. Myoglobin’s molecular weight is 16.7 kDa, and it is the primary oxygen-carrying pigment of muscle tissues. The binding of oxygen in myoglobin is different from the cooperative oxygen binding in hemoglobin, since positive collaboration is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is uninfluenced by the oxygen pressure in the surrounding tissue. Myoglobin is frequently referred to as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve. Different organisms are able to hold their breaths longer due to high concentrations of myoglobin in their muscle cells. Myoglobin is responsible for the pigments that make meat red. The color of the meat is partly determined by the charge of the iron atom in myoglobin and the oxygen attached to it. Myoglobin is found in Type I muscle, Type II A and Type II B, but it is mostly deemed that myoglobin is not found in smooth muscle. Myoglobin is discharged from damaged muscle tissue (rhabdomyolysis), which contains very high concentrations of myoglobin. Even though the released myoglobin is filtered by the kidneys, it is toxic to the renal tubular epithelium and thus may cause acute renal failure.

Description:
Human Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa.
Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.

Source:
Human Cardiac Tissues

Physical Appearance:
Sterile Filtered red solution.

Formulation:
The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.2µM membrane.

Stability:
Human Myoglobin should be stored at 2-8°C.

Purity:
Greater than 96.0%.

Human Virus Test:
Starting material donor tested and certified negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies. Product tested and found negative for HTLV antibodies.

Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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人类肌红蛋白(Human Myoglobin)由上海希美化学有限公司为您提供,货号PRO-565,规格:200μg/1mg/10mg,CAS号:,如您想了解更多关于人类肌红蛋白(Human Myoglobin)价格、人类肌红蛋白(Human Myoglobin)结构式、批发、用途等信息,欢迎咨询。除供应人类肌红蛋白(Human Myoglobin)外,还可为您提供大鼠肌红蛋白(MYO/MB)ELISA Kit、重组人肌红蛋白(Recombinant Human Myoglobin)等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,上海希美化学客户服务电话,售前、售后均可联系。
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