供货周期: | 一周 |
品牌: | Prospec-Tany |
规格: | 250μg/1mg/5mg |
货号: | HOR-235 |
CAS号: |
Catalogue Number | HOR-235 |
Synonyms | Somatoliberin, Growth hormone-releasing factor, GRF, Growth hormone-releasing hormone, GHRH, Somatocrinin, Somatorelin, Sermorelin, GHRF, MGC119781. |
Introduction |
Growth-hormone-releasing hormone (GHRH), also known as growth-hormone-releasing factor (GRF or GHRF) or somatocrinin, is a 44-amino acidpeptide hormoneproduced in the arcuate nucleusof the hypothalamus. GHRH is released from neurosecretory nerve terminals of these arcuate neurons, and is carried by the hypothalamo-hypophysial portal circulation to the anterior pituitary glandwhere it stimulates growth hormone(GH) secretion. GHRH also stimulates the production of GH. GHRH is released in a pulsatile manner, stimulating similar pulsatile release of GH. In addition, GHRH also promotes slow-wave sleepdirectly. |
Description |
Growth Hormone Releasing Hormone Human Synthetic is a single, non-glycosylated, polypeptide chain containing 29 amino acids and having a molecular mass of 3358.9 Dalton. Corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing hormone consisting of 44 amino acid residues. The GHRH is purified by proprietary chromatographic techniques. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | The GHRH peptide (1mg/ml) was lyophilized after extensive dialyses against 1.7 mg sodium phosphate buffer (0.1 mg sodium phosphate monobasic & 1.6 mg sodium phosphate dibasic). |
Solubility | It is recommended to reconstitute the lyophilized GHRH in sterile 18MΩ-cm H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions. The GHRH is also soluble in 1% Acetic acid at a concentration of >1mg/ml to give a clear, colorless solution. |
Stability |
Lyophilized Growth Hormone Releasing Hormone although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GHRF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Purity |
Greater than 98.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Amino Acid Sequence |
The free base of sermorelin has the empirical formula C149H246N 44O42S. Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2. |
Biological Activity | GHRH increases plasma growth hormone concentrations by directly stimulating the anterior pituitary gland to release natural human growth hormone. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
相关产品
人胃泌素(Gastrin)ELISA试剂盒Human Gastrin ELISA Kit
人胃动素(MTL)ELISA试剂盒Human MTL ELISA Kit
人胃蛋白酶(PG)ELISA试剂盒Human Pepsin ELISA Kit
人维生素D3(VD3)ELISA试剂盒Human VD3 ELISA kit
人维生素B1(VB1)ELISA试剂盒Human Vitamin B1 ELISA kit
人晚期氧化蛋白产物(AOPP)ELISA试剂盒Human AOPP ELISA Kit
人晚期糖基化终末产物受体(RAGE/AGER)ELISA试剂盒Human RAGE/AGER ELISA Kit
人晚期糖基化终末产物(AGEs)ELISA试剂盒Human AGEs ELISA Kit
人唾液酸(SA)ELISA试剂盒Human,SA ELISA Kit
人褪黑素(MT)ELISA试剂盒Human,MT ELISA Kit
人透明质酸(HA)ELISA试剂盒Human,HA ELISA Kit
人同型半胱氨酸(Hcy)ELISA试剂盒Human,Hcy ELISA试剂盒
人铁蛋白(FE)ELISA试剂盒Human,FE ELISA试剂盒
人天门冬氨酸氨基转移酶(AST)ELISA试剂盒Human AST ELISA试剂盒
人糖原磷酸化酶同工酶BB(GP-BB)ELISA试剂盒Human GP-BB ELISA试剂盒
详细地址
关注
拨打电话
留言咨询