供货周期: | 一周 |
品牌: | |
规格: | 10μg/50μg/1mg |
货号: | ENZ-361 |
CAS号: |
GRX1 Yeast
Glutaredoxin 1 Yeast Recombinant
Catalog No. ENZ-361
Synonyms:
Thioltransferase, GRX, GLRX1, GRX1, GRX-1, GLRX-1, Glutathione-dependent oxidoreductase 1, Glutaredoxin 1.
Introduction:
GRX1 has a glutathione-disulfide oxidoreductase activity in the presence of nadph and glutathione reductase. Reduces low molecular weight disulfides and proteins.
Glutaredoxin is a glutathione (GSH)-dependent hydrogen donor for ribonucleotide reductase and also catalyzes glutathione-disulfide oxidoreduction reactions in the presence of NADPH and glutathione reductase. GRX1 is multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity. The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage.
Description:
Glutaredoxin Saccharamyces cerevisiae Recombinant conaining 6x His tag at C-Terminus produced in E.Coli is a single, non-glycosylated, Polypeptide chain having a molecular mass of 16 kDa.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear colorless solution.
Formulation:
Glutaredoxin solution contains 25mM Tris-HCl pH-7.5 & 0.01% Na Azide.
Stability:
1 week at 2-10°C. For long term store at -20 to -80°C.
Purity:
Greater than 90% as determined by SDS-PAGE.
Applications:
ELISA, Western Blot, strongly binds to glutathione, reduced and oxidized.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals
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