供货周期: | 一周 |
品牌: | |
规格: | 250000IU/750000IU/1.5MIU |
货号: | ENZ-315 |
CAS号: |
Streptokinase
Streptokinase Recombinant
Catalog No. ENZ-315
Synonyms:
Streptokinase, SK.
Introduction:
Streptokinase is an extracellular metallo-enzymeproduced by beta-haemolytic streptococcusand is used as an effective and cheap clot-dissolving medicationin some cases of myocardial infarction(heart attack) and pulmonary embolism.
It belongs to a group of medications known as fibrinolytics, and works by activating plasminogenthrough cleavage to produce plasmin.
Description:
Streptokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 414 amino acids and having a molecular weight of 47 kd.
The Streptokinase is purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:
The protein (1.5 MIU) was lyophilized from a sterile solution containing 12.5 mg HSA, 2.3 mg Sodium phosphate dibasic, 0.55 mg sodium phosphate monobasic buffer and 4.2 mg Sodium glutamate monohydrate.
Solubility:
It is recommended to reconstitute the lyophilized Streptokinase in sterile 18MΩ-cm H2O.
Stability:
Lyophilized Streptokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Streptokinase should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
Purity:
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Biological Activity:
One unit will liquify a standard clot of fibrinogen, plasminogen and thrombin at pH7.5 at 37°C in 10 min.
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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