供货周期: | 一周 |
品牌: | |
规格: | 2μg/5μg/10μg |
货号: | PRO-513 |
CAS号: |
IRF4 Human
IRF4 Human Recombinant
Catalog No. PRO-513
Synonyms:
Interferon regulatory factor 4, IRF-4, Lymphocyte-specific interferon regulatory factor, LSIRF, NF-EM5, Multiple myeloma oncogene 1, IRF4, MUM1.
Introduction:
IRF4 is a transcriptional activator, belonging to the IRF family. It binds to the interferon- stimulated response element (ISRE) of the MHC Class I promoter (but is not induced by Interferons). IRF4 binds the immunoglobulin lambda light chain enhancer, together with Pu.1. It most likely plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
IRF4 / MUM1 is expressed in the nuclei and cytoplasm of plasma cells and a small percentage of germinal center (GC) B cells mainly located in the "light zone". Its morphologic spectrum ranged from that of centrocyte to that of a plasmablast/plasma cell, and it displayed a phenotype (MUM1+/Bcl-6/Ki67 ) different from that of most GC B cells (MUM1 /Bcl-6+/Ki67+) and mantle B cells (MUM1 /Bcl-6 /Ki67 ).
Description:
IRF4 Human Recombinant (aa 144-451) expressed in E.coli. IRF4 is antibody reactive. The IRF4 is fused to a GST tag and purified by proprietary chromatographic techniques.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered clear solution.
Formulation:
IRF-4 in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability:
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications:
• ELISA
• Inhibition Assays
• Western Blotting
Usage:
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
相关产品
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
大鼠酸性磷酸酶(ACP)ELISA Kit
大鼠胆囊收缩素/缩胆囊素八肽(CCK-8)ELISA Kit
人瘦素(LEP)ELISA Kit
重组人半乳糖凝集素16/LGALS16 Human
重组人半乳糖凝集素8/Human LGALS8 His
重组人半乳糖凝集素3/Human LGALS3 His
重组人卵泡抑素/Human FST His
重组人β防御素118/DEFB118 Human
重组人心肌营养素1/CTF1 Human
特级新生牛血清(无支原体)
超级新生牛血清(无支原体)
优级胎牛血清(无支原体)
特级新生牛血清(无噬菌体低内毒素)
详细地址
关注
拨打电话
留言咨询