重组人肌红蛋白（Recombinant Human Myoglobin）|5µg|PRO-336-上海高创化学科技有限公司

产品详情

重组人肌红蛋白
Recombinant Human Myoglobin

Synonyms

Myoglobin, MB, PVALB, MGC13548.

Introduction

Myoglobin is a member of the globin superfamily and can be found in skeletal and cardiac muscles. It is a haemoprotein that contributs to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. Myoglobin has a single-chain globular structure of 153 amino acids, containing a heme prosthetic group (iron-containing porphyrin) in the core around which the remaining apoprotein folds. Myoglobin has 8 alpha helices and a hydrophobic core. Myoglobin’s molecular weight is 16.7 kDa, and it is the primary oxygen-carrying pigment of muscle tissues. The binding of oxygen in myoglobin is different from the cooperative oxygen binding in hemoglobin, since positive collaboration is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is uninfluenced by the oxygen pressure in the surrounding tissue. Myoglobin is frequently referred to as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve. Different organisms are able to hold their breaths longer due to high concentrations of myoglobin in their muscle cells. Myoglobin is responsible for the pigments that make meat red. The color of the meat is partly determined by the charge of the iron atom in myoglobin and the oxygen attached to it. Myoglobin is found in Type I muscle, Type II A and Type II B, but it is mostly deemed that myoglobin is not found in smooth muscle. Myoglobin is discharged from damaged muscle tissue (rhabdomyolysis), which contains very high concentrations of myoglobin. Even though the released myoglobin is filtered by the kidneys, it is toxic to the renal tubular epithelium and thus may cause acute renal failure.

Description

Myoglobin Human Recombinant produced in E.Coli is a non-glycosylated polypeptide chain having a molecular mass of 17.67 kDa. The Myoglobin is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered brownish solution.

Formulation

The sterile solution contains phosphate-buffered saline (pH 7.4) and 0.05% NaN3.

Stability

Myoglobin should be stored at 4°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please do not freeze.

Purity

Greater than 95.0% as determined by(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Usage

Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» Myo Human w/o H

» Myoglobin Human

重组人肌红蛋白（Recombinant Human Myoglobin）由上海高创化学科技有限公司为您提供，货号PRO-336，规格：5µg，CAS号：，如您想了解更多关于重组人肌红蛋白（Recombinant Human Myoglobin）价格、重组人肌红蛋白（Recombinant Human Myoglobin）结构式、批发、用途等信息，欢迎咨询。除供应重组人肌红蛋白（Recombinant Human Myoglobin）外，还可为您提供人肌红蛋白(MYO/MB)ELISA Kit、人肌红蛋白|Human Myoglobin等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。

供货周期：	7天
品牌：	Prospec-Tany
型号：	5µg
货号：	PRO-336