| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 2µg |
| 货号： | PRO-474 |
| CAS号： |
ADAM12 Human
A Disintegrin and Metalloproteinase Domain 12 S-Isoform Human Recombinant
Catalog No. PRO-474
Synonyms:
Meltrin alpha, MCMP, MLTN, MLTNA, MCMPMltna, ADAM metallopeptidase domain 12, ADAM 12, ADAM12.
Introduction:
ADAM12 is part of the A Disintegrin and Metalloprotease protein family wjich are membrane-anchored proteins structurally related to snake venom disintegrins, and are involved in a range of biological processes concerning cell-cell and cell-matrix interactions, including fertilization, muscle development, and eurogenesis.
ADAM12 has 2 alternatively spliced transcripts, a shorter/soluble secreted form called S-isoform and a longer membrane-bound form call L isoform. The S isoform is found to stimulate myogenesis. The short & soluble isoform lacks the transmembrane and cytoplasmic domains. ADAM12 S Isoform expression is limited to the placenta, embryo and foetus although levels have been detected in some tumour cell lines. ADAM12 takes part in skeletal muscle regeneration, specifically at the onset of cell fusion. ADAM12 is involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (by similarity).
Description:
ADAM12 Short/soluble isoform Human Recombinant fused to N-terminal His-Tag produced in E.Coli is a single, non-glycosylated polypeptide chain containing 531 amino acids (208-738) and having a molecular mass of 60 kDa.
Source:
Escherichia Coli.
Physical Appearance:
Sterile Filtered colorless solution.
Formulation:
The ADAM12 solution contains PBS and 50% Glycerol.
Stability:
ADAM12 although stable 4°C for 4 weeks, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Purity:
Greater than 95.0% as determined by SDS-PAGE.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
» ADAM10 Human
相关产品
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
大鼠酸性磷酸酶(ACP)ELISA Kit
大鼠胆囊收缩素/缩胆囊素八肽(CCK-8)ELISA Kit
人瘦素(LEP)ELISA Kit
重组人半乳糖凝集素16/LGALS16 Human
重组人半乳糖凝集素8/Human LGALS8 His
重组人半乳糖凝集素3/Human LGALS3 His
重组人卵泡抑素/Human FST His
重组人β防御素118/DEFB118 Human
重组人心肌营养素1/CTF1 Human
特级新生牛血清（无支原体）
超级新生牛血清（无支原体）
优级胎牛血清（无支原体）
特级新生牛血清（无噬菌体低内毒素）
工商信息
信息已认证
联系方式
详细地址
关注
拨打电话
留言咨询
