| SKU:K1315 | M. Wt:521.53 | ||
| Formula:C25H30F3N5O4 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:908115-27-5 | Synonyms:N/A | ||
| Chemical NameN/A | |||
| 供货周期： | 7天 |
| 品牌： | |
| 型号： | 2mg |
| 货号： | K1315 |
| CAS号： | 908115-27-5 |
| SKU:K1315 | M. Wt:521.53 | ||
| Formula:C25H30F3N5O4 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:908115-27-5 | Synonyms:N/A | ||
| Chemical NameN/A | |||
| Description | PF-04929113 (SNX-5422) | |||||
|---|---|---|---|---|---|---|
| Targets | HSP90 | |||||
| IC50 | 41 nM | |||||
| In vitro | As a selective HSP90 inhibitor, PF-04929113 (SNX-5422) can potently inhibit HSP90 with Kd of 41 nM. PF-04929113 (SNX-5422) also shows inhibition to Her-2 degradation with IC50 of 37 nM.PF-04929113 can inhibit cell lines MCF-7, SW620, K562, SK-MEL-5, and SK-MEL-5 with IC50 of 16 nM, 19 nM, 23 nM, 25 nM, and 51 nM. | |||||
| In vivo | PF-04929113 administered orally twice a week is well tolerated and inhibits its intended target Hsp90. | |||||
| Clinical Trials | N/A | |||||
| Features | N/A | |||||
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
大鼠酸性磷酸酶(ACP)ELISA Kit
大鼠胆囊收缩素/缩胆囊素八肽(CCK-8)ELISA Kit
人瘦素(LEP)ELISA Kit
重组人半乳糖凝集素16/LGALS16 Human
重组人半乳糖凝集素8/Human LGALS8 His
重组人半乳糖凝集素3/Human LGALS3 His
重组人卵泡抑素/Human FST His
重组人β防御素118/DEFB118 Human
重组人心肌营养素1/CTF1 Human
特级新生牛血清（无支原体）
超级新生牛血清（无支原体）
优级胎牛血清（无支原体）
特级新生牛血清（无噬菌体低内毒素）
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