SKU:K1321 | M. Wt:305.17 | ||
Formula:C14H13BrN2O | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:65678-07-1 | Synonyms:N/A | ||
Chemical NameN/A |
供货周期: | 7天 |
品牌: | |
型号: | 2mg |
货号: | K1321 |
CAS号: | 65678-07-1 |
SKU:K1321 | M. Wt:305.17 | ||
Formula:C14H13BrN2O | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:65678-07-1 | Synonyms:N/A | ||
Chemical NameN/A |
Description | AG-1024 (Tyrphostin) | |||||
---|---|---|---|---|---|---|
Targets | IGF-1R | |||||
IC50 | 400 nM | |||||
In vitro | Tyrphostin AG1024 can inhibit IGF-1R with IC50 of around 400 nM. By inhibiting insulin-like growth factor 1 receptor and insulin receptor, Tyrphostin AG1024 arrested melanoma cell growth. Tyrphostin AG1024 inhibited the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and restored pRb tumor suppressive function. | |||||
In vivo | Administration of AG-1024 at a dose of 30 ug for 10 days significantly inhibits the tumor growth of Ba/F3-p210 xenograft in mice. | |||||
Clinical Trials | N/A | |||||
Features | N/A |
重组人肌球蛋白轻链2(Recombinant Human MYL2)
重组大鼠抵抗素(Rat Resistin)
大鼠酸性磷酸酶(ACP)ELISA Kit
大鼠胆囊收缩素/缩胆囊素八肽(CCK-8)ELISA Kit
人瘦素(LEP)ELISA Kit
重组人半乳糖凝集素16/LGALS16 Human
重组人半乳糖凝集素8/Human LGALS8 His
重组人半乳糖凝集素3/Human LGALS3 His
重组人卵泡抑素/Human FST His
重组人β防御素118/DEFB118 Human
重组人心肌营养素1/CTF1 Human
特级新生牛血清(无支原体)
超级新生牛血清(无支原体)
优级胎牛血清(无支原体)
特级新生牛血清(无噬菌体低内毒素)
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