| SKU:K1325 | M. Wt:489.53 | ||
| Formula:C28H23N7O2 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:900185-02-6 | Synonyms:N/A | ||
| Chemical NameN/A | |||
| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 2mg |
| 货号： | K1325 |
| CAS号： | 900185-02-6 |
| SKU:K1325 | M. Wt:489.53 | ||
| Formula:C28H23N7O2 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:900185-02-6 | Synonyms:N/A | ||
| Chemical NameN/A | |||
| Description | PIK-294 | |||||
|---|---|---|---|---|---|---|
| Targets | p110-beta | p110-gamma | p110-delta | |||
| IC50 | 490 nM | 160 nM | 10 nM | |||
| In vitro | PIK-294 can inhibit p110-beta, p110-gamma and p110-delta with IC50 of 490 nM, 160 nM and 10 nM. PIK-294 was designed based on the inhibitor PI-103, a potent PI3K inhibitor. PIK-294 projects a m-phenol into ATP binding site. PIK-294 is 20- to 60-fold more potent than the parent compound, PIK-293. PIK-294 is one of the most potent p110delta-selective inhibitors that has been reported. | |||||
| In vivo | N/A | |||||
| Clinical Trials | N/A | |||||
| Features | N/A | |||||
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