SKU:K1326 | M. Wt:391.55 | ||
Formula:C26H33NO2 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:154229-18-2 | Synonyms:CB 7630, CB-7630 | ||
Chemical NameN/A |
供货周期: | 一周 |
品牌: | |
规格: | 2mg |
货号: | K1326 |
CAS号: | 154229-18-2 |
SKU:K1326 | M. Wt:391.55 | ||
Formula:C26H33NO2 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:154229-18-2 | Synonyms:CB 7630, CB-7630 | ||
Chemical NameN/A |
Description | Abiraterone Acetate (CB7630) | |||||
---|---|---|---|---|---|---|
Targets | cytochrome P45017alpha | |||||
IC50 | 4nM | |||||
In vitro | Abiraterone (17-(3-pyridyl)androsta-5,16-dien-3beta-ol, 1) is a potent inhibitor (IC50 4 nM for hydroxylase) of human cytochrome P45017alpha. [1] Abiraterone acetate is a selective, irreversible inhibitor of CYP17 and can suppress adrenal synthesis of androgen precursors, and possibly in situ steroidogenesis in the tumor microenvironment.Abiraterone inhibits both testicular and extratesticular androgen synthesis.[2] | |||||
In vivo | N/A | |||||
Clinical Trials | N/A | |||||
Features | N/A |
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