SKU:K1347 | M. Wt:468.84 | ||
Formula:C23H15ClF2N4O3 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:1174046-72-0 | Synonyms:N/A | ||
Chemical NameN/A |
供货周期: | 一周 |
品牌: | |
规格: | 2mg |
货号: | K1347 |
CAS号: | 1174046-72-0 |
SKU:K1347 | M. Wt:468.84 | ||
Formula:C23H15ClF2N4O3 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:1174046-72-0 | Synonyms:N/A | ||
Chemical NameN/A |
Description | BMS 794833 | |||||
---|---|---|---|---|---|---|
Targets | Met | VEGFR2 | ||||
IC50 | 1.7 nM | 15 nM | ||||
In vitro | BMS794833 also inhibits Met receptor activated gastric carcinoma cell line, GTL-16, with IC50 of 39 nM. | |||||
In vivo | In GTL-16 human gastric tumor xenografts model, BMS798433 shows greater than 50% TGI for at least one tumor doubling time with no overt toxicity observed during 14 days. BMS798433 also shows complete tumor stasis at a dose of 25 mg/kg against U87 glioblastoma model. [1] | |||||
Clinical Trials | N/A | |||||
Features | N/A |
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