SKU:K1359 | M. Wt:295.29 | ||
Formula:C12H15N5O3.H2O | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:209216-23-9 | Synonyms:Baraclude | ||
Chemical NameN/A |
供货周期: | 一周 |
品牌: | |
规格: | 2mg |
货号: | K1359 |
CAS号: | 209216-23-9 |
SKU:K1359 | M. Wt:295.29 | ||
Formula:C12H15N5O3.H2O | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:209216-23-9 | Synonyms:Baraclude | ||
Chemical NameN/A |
Description | Entecavir hydrate | |||||
---|---|---|---|---|---|---|
Targets | N/A | |||||
IC50 | N/A | |||||
In vitro | Entecavir is an oral antiviral drug with selective activity against hepatitis B virus (HBV). Entecavir (ETV) exhibits potent antiviral activity in patients chronically infected with wild-type or lamivudine (3TC)-resistant (3TC(r)) hepatitis B virus (HBV). | |||||
In vivo | All doses of entecavir (0.05 mg, 0.1 mg, 0.5 mg, and 1.0 mg) showed a pronounced suppression of replication of the HBV. Entecavir reduced HBV DNA by an additional 0.97 log(10) at the 0.1-mg/day dose and an additional 1.28 log(10) at the 0.5-mg/day dose. In this 28-day study of entecavir a pronounced decrease of HBV DNA was observed and there were no significant side effects in entecavir patients in comparison with placebo-treated patients. | |||||
Clinical Trials | N/A | |||||
Features | N/A |
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