Entecavir hydrate

Entecavir hydrate

参考价:¥1298
供货周期: 一周
品牌:
规格: 2mg
货号: K1359
CAS号: 209216-23-9
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SKU:K1359   M. Wt:295.29  
Formula:C12H15N5O3.H2O   Solubility:No  
Purity:>99%   Storage:2 years at -20 degrees centigrade  
CAS No.:209216-23-9   Synonyms:Baraclude  
Chemical NameN/A
Biological Activity
Description Entecavir hydrate
Targets N/A        
IC50 N/A        
In vitro Entecavir is an oral antiviral drug with selective activity against hepatitis B virus (HBV). Entecavir (ETV) exhibits potent antiviral activity in patients chronically infected with wild-type or lamivudine (3TC)-resistant (3TC(r)) hepatitis B virus (HBV).
In vivo All doses of entecavir (0.05 mg, 0.1 mg, 0.5 mg, and 1.0 mg) showed a pronounced suppression of replication of the HBV. Entecavir reduced HBV DNA by an additional 0.97 log(10) at the 0.1-mg/day dose and an additional 1.28 log(10) at the 0.5-mg/day dose. In this 28-day study of entecavir a pronounced decrease of HBV DNA was observed and there were no significant side effects in entecavir patients in comparison with placebo-treated patients.
Clinical Trials N/A
Features N/A

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