| SKU:K1372 | M. Wt:572.59 | ||
| Formula:C21H21FN6O.2C3H6O3 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:852433-84-2 | Synonyms:CHIR-258 Dilactic acid | ||
| Chemical NameN/A | |||
| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 2mg |
| 货号： | K1372 |
| CAS号： | 852433-84-2 |
| SKU:K1372 | M. Wt:572.59 | ||
| Formula:C21H21FN6O.2C3H6O3 | Solubility:No | ||
| Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
| CAS No.:852433-84-2 | Synonyms:CHIR-258 Dilactic acid | ||
| Chemical NameN/A | |||
| Description | Dovitinib Dilactic acid (TKI258 Dilactic acid) | |||||
|---|---|---|---|---|---|---|
| Targets | FLT3 | c-KIT | ||||
| IC50 | 1 nM | 2 nM | ||||
| In vitro | Dovitinib Dilactic acid (TKI258 Dilactic acid) is a highly potent, novel multitargeted growth factor receptor kinase inhibitor with IC50 of 1, 2, 10, 8, 27, 36 nM for FLT3, c-KIT, VEGFR1/2/3, PDGFR? and CSF-1R. Dovitinib Dilactic acid (TKI258 Dilactic acid) potently inhibits FGFR3 with an inhibitory concentration of 50% (IC50) of 5 nM in in vitro kinase assays and selectively inhibited the growth of B9 cells and human myeloma cell lines expressing wild-type (WT) or activated mutant FGFR3. | |||||
| In vivo | ||||||
| Clinical Trials | N/A | |||||
| Features | N/A | |||||
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