| SKU:K1386 | M. Wt:414.49 | ||
| Formula:C24H30O6 | Solubility:DMSO <1 mg/mL, Water <1 mg/mL, Ethanol <1 mg/mL | ||
| Purity:>99% | Storage:2 years at -20°C Powder | ||
| CAS No.:107724-20-9 | Synonyms:Inspra | ||
| Chemical NameN/A | |||
| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 10mg |
| 货号： | K1386 |
| CAS号： | 107724-20-9 |
| SKU:K1386 | M. Wt:414.49 | ||
| Formula:C24H30O6 | Solubility:DMSO <1 mg/mL, Water <1 mg/mL, Ethanol <1 mg/mL | ||
| Purity:>99% | Storage:2 years at -20°C Powder | ||
| CAS No.:107724-20-9 | Synonyms:Inspra | ||
| Chemical NameN/A | |||
| Description | Eplerenone | |||||
|---|---|---|---|---|---|---|
| Targets | mineralocorticoid receptor | |||||
| IC50 | N/A | |||||
| In vitro | Eplerenone is a specific mineralocorticoid receptor blocker. Eplerenone can reduce the risk of cardiovascular death in people with heart failure and left ventricular dysfunction.[1] | |||||
| In vivo | Eplerenone reduced atherosclerotic lesion size by 51% only in early ATS.In peritoneal macrophages obtained from these mice, eplerenone reduced messenger RNA expression of pro-inflammatory markers, interleukin 6, tumor necrosis factor alpha, monocyte chemotactic protein 1, and increased anti-inflammatory marker arginase 1 to a greater extent in early compared with advanced ATS. [2] | |||||
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