SKU:K1390 | M. Wt:338.4 | ||
Formula:C20H22N2O3 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:546141-08-6 | Synonyms:KDS-4103 | ||
Chemical NameN/A |
供货周期: | 一周 |
品牌: | |
规格: | 5mg |
货号: | K1390 |
CAS号: | 546141-08-6 |
SKU:K1390 | M. Wt:338.4 | ||
Formula:C20H22N2O3 | Solubility:No | ||
Purity:>99% | Storage:2 years at -20 degrees centigrade | ||
CAS No.:546141-08-6 | Synonyms:KDS-4103 | ||
Chemical NameN/A |
Description | URB597 | |||||
---|---|---|---|---|---|---|
In vitro | URB597 is a highly selective O-arylcarbamate inhibitor of intracellular FAAH activity. | |||||
In vivo | Administration of the selective FAAH inhibitor URB597 (cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester; 0.3 mg/kg i.p.) increases anandamide levels in the brain of rats and wild-type mice but has no such effect in FAAH-null mutants. URB597 enhances the hypothermic actions of anandamide (5 mg/kg i.p.) in wild-type mice but not in FAAH-null mice. URB597 does not alter the hypophagic response elicited by OEA (5 and 10 mg/kg i.p.), which is mediated by activation of peroxisome proliferator-activated receptor type-alpha. |
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