| 供货周期： | 一周 |
| 品牌： | |
| 规格： | 2mg |
| 货号： | K1397 |
| CAS号： | 173334-58-2 |
| SKU:K1397 | M. Wt:609.83 | ||
| Formula:C30H53N3O6.1/2C4H4O4 | Solubility:DMSO 122 mg/mL, Water 122 mg/mL, Ethanol 122 mg/mL | ||
| Purity:>99% | Storage:2 years at -20°C Powder | ||
| CAS No.:173334-58-2 | Synonyms:N/A | ||
| Chemical Name(2S,4S,5S,7S)-7-(4-methoxy-3-(3-methoxypropoxy)benzyl)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-8-methylnonanamide hemifumarate | |||
| Description | Aliskiren hemifumarate is a direct renin inhibitor with IC50 of 1.5 nM. Aliskiren hemifumarate can bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans. | |||||
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