Letrozole(aromatase抑制剂)

Letrozole(aromatase抑制剂)

参考价:¥748
供货周期: 一周
品牌:
规格: 10mg
货号: K1401
CAS号: 112809-51-5
上海高创化学科技有限公司
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SKU:K1401   M. Wt:285.3  
Formula:C17H11N5   Solubility:DMSO 57 mg/mL, Water <1 mg/mL, Ethanol <1 mg/mL  
Purity:>99%   Storage:2 years at -20°C Powder  
CAS No.:112809-51-5   Synonyms:CGS 20267  
Chemical NameN/A
Biological Activity
Description Letrozole
Targets          
IC50          
In vitro Letrozole is a third generation inhibitor of aromatase with IC50 of 0.07-20 nM. Letrozole potently inhibits aromatase derived from a variety of different sources including human placental microsomes, particulate fractions of human breast cancer, rat ovarian microsomes, MCF-7 cells transfected with aromatase (MCF-7Ca), JEG-3 human choriocarcinoma cells , CHO cells, hamster ovarian tissue, and particulate fractions of human breast cancer with IC50 of 11, 2, 7, 0.07, 0.07, 1.4, 20 and 0.8 nM.
In vivo N/A
Clinical Trials N/A
Features N/A

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