SKU:K1407 | M. Wt:243.22 | ||
Formula:C9H13N3O5 | Solubility:DMSO 1 mg/mL, Water 48 mg/mL, Ethanol <1 mg/mL | ||
Purity:>99% | Storage:2 years at -20°C Powder | ||
CAS No.:147-94-4 | Synonyms:N/A | ||
Chemical NameN/A |
供货周期: | 一周 |
品牌: | |
规格: | 50mg |
货号: | K1407 |
CAS号: | 147-94-4 |
SKU:K1407 | M. Wt:243.22 | ||
Formula:C9H13N3O5 | Solubility:DMSO 1 mg/mL, Water 48 mg/mL, Ethanol <1 mg/mL | ||
Purity:>99% | Storage:2 years at -20°C Powder | ||
CAS No.:147-94-4 | Synonyms:N/A | ||
Chemical NameN/A |
Description | Cytarabine | |||||
---|---|---|---|---|---|---|
Targets | ||||||
IC50 | ||||||
In vitro | Cytarabine (AraC) is phosphorylated into a triphosphate form (Ara-CTP) involving deoxycytidine kinase (dCK), which competes with dCTP for incorporation into DNA, and then blocks DNA synthesis by inhibiting the function of DNA and RNA polymerases. Cytarabine displays a higher growth inhibitory activity towards wild-type CCRF-CEM cells compared to other acute myelogenous leukemia (AML) cells with IC50 of 16 nM. | |||||
In vivo | N/A | |||||
Clinical Trials | N/A | |||||
Features | N/A |
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