Ezetimibe

Ezetimibe

参考价:¥1067
供货周期: 一周
品牌:
规格: 50mg
货号: K1408
CAS号: 163222-33-1
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SKU:K1408   M. Wt:409.4  
Formula:C24H21F2NO3   Solubility:DMSO 82 mg/mL, Water <1 mg/mL, Ethanol 82 mg/mL  
Purity:>99%   Storage:2 years at -20°C Powder  
CAS No.:163222-33-1   Synonyms:Zetia  
Chemical NameN/A
Biological Activity
Description Ezetimibe
Targets          
IC50          
In vitro Ezetimibe (Zetia) is a compound that lowers cholesterol. Ezetimibe (Zetia) acts by decreasing cholesterol absorption in the intestine. Ezetimibe (Zetia) may be used alone, when other cholesterol-lowering medications are not tolerated, or together with statins when statins alone do not control cholesterol. Ezetimibe localises at the brush border of the small intestine, where ezetimibe (Zetia) inhibits the absorption of cholesterol from the intestine. Specifically, ezetimibe (Zetia) appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes.
In vivo N/A
Clinical Trials N/A
Features N/A

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