重组人Long R3胰岛素样生长因子1（Human Long R3 IGF1）|500ug|cyt-022-上海高创化学科技有限公司

产品详情

Catalogue Number

CYT-022

Synonyms

R3 IGF1, R3 IGF-1, R3IGF1, R3IGF-1, LONG IGF1, LONG IGF-1, LONG R3 IGF1, LONG R3IGF1, LONG R3 IGF-1, LONG R3IGF-1.

Introduction

IGF-1 (Insulin-like growth factor-1) is a major hormonal mediator of statural growth. Under regular circumstances, GH (growth hormone) binds to its receptor in the liver, and other tissues, and stimulates the synthesis/secretion of IGF-1. In target tissues, the Type 1 IGF receptor, that is homologous to the insulin receptor, is activated by IGF-1, leading to intracellular signaling which stimulates multiple processes leading to statural growth. IGF-1 metabolic actions are partly directed at stimulating the uptake of glucose, fatty acids, and amino acids so that metabolism supports growing tissues.

Description

The LR3 is a long-term analog of human IGF-1, specifically designed and manufactured for mammalian cell culture to support large-scale manufacturing of recombinant biopharmaceuticals.
Recombinant Human LR3 Insulin Like Growth Factor-1 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 83 amino acids and having a molecular mass of 9.1kDa.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 1xPBS.

Solubility

It is recommended to reconstitute the lyophilized LR3 IGF1 in sterile 18M-cm H₂O at a concentration of 100μg/ml, which can then be further diluted to other aqueous solutions.

Stability

Lyophilized LR3 IGF1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution the LR3 IGF1 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity

Greater than 95.0% as determined by SDS-PAGE and HPLC.

Amino acid sequence

MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIV DECCFRSCDLRRLEMYCAPLKPAKSA.

Biological Activity

The ED50 as determined by the stimulation of protein synthesis in L6 myoblasts is less then 1ng/ml, corresponding to a specific activity of 1,000,000 units/mg.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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重组人Long R3胰岛素样生长因子1（Human Long R3 IGF1）由上海高创化学科技有限公司为您提供，货号cyt-022，规格：500ug，CAS号：，如您想了解更多关于重组人Long R3胰岛素样生长因子1（Human Long R3 IGF1）价格、重组人Long R3胰岛素样生长因子1（Human Long R3 IGF1）结构式、批发、用途等信息，欢迎咨询。除供应重组人Long R3胰岛素样生长因子1（Human Long R3 IGF1）外，还可为您提供重组人胰岛素样生长因子1-N15|Human IGF1 N15等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，上海高创客户服务电话，售前、售后均可联系。

供货周期：	7天
品牌：	Prospec-Tany
型号：	500ug
货号：	cyt-022