重组人中脑星形胶质细胞衍生神经营养因子|Human MANF|5ug|cyt-141-上海高创化学科技有限公司

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重组人中脑星形胶质细胞衍生神经营养因子|Human MANF

Recombinant Human Mesencephalic Astrocyte-Derived Neurotrophic Factor

Catalogue Number	CYT-141
Synonyms	Mesencephalic astrocyte-derived neurotrophic factor, Protein ARMET, ARP, arginine-rich mutated in early stage tumors, Arginine-rich protein.
Introduction	MANF is a 20kDa protein which belongs to the ARMET family. MANF was originally known as an arginine-rich region protein which was extremely mutated in a large number of tumors. MANF Expression is induced during ER stress, signifying that MANF takes part in protein quality control during ER stress.
Description	MANF Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids and having a molecular mass of 18.1 kDa. The MANF is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	Filtered (0.2μm) and lyophilized from a concentrated (1mg/ml) solution in 1×PBS, pH7.4.
Solubility	It is recommended to reconstitute the lyophilized MANF in sterile 18M-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized MANF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MANF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity	Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino acid sequence	LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDA ATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKIL DDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL.
Biological Activity	The ED50 was determined by its ability to stimulate the proliferation of rat C6 cells is typically 15-25 μg/ml.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products	? 重组人中脑星形胶质细胞衍生神经营养因子/MANF Human, His ? 重组小鼠中脑星形胶质细胞衍生神经营养因子/MANF Mouse ? 重组大鼠中脑星形胶质细胞衍生神经营养因子/MANF Rat

供货周期：	一周
品牌：	Prospec-Tany
规格：	5ug
货号：	cyt-141
CAS号：