供货周期: | 一周 |
品牌: | Prospec-Tany |
规格: | 5ug |
货号: | cyt-152 |
CAS号: |
ProSpec(蛋白质专家)是以色列一家具有超过16年历史的,专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下,ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高,其蛋白产品不仅纯度高、生物活性高,价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。
ProSpec向客户提供蛋白质产品、服务和技术授权。因为创新的产品、卓越的客户服务和对细节的注重,ProSpec在科学界建立了良好的信誉,具有广泛的客户群,包括世界各地的学术、政府研究机构,生物技术和制药企业以及医院和基准实验室。
热门产品
Adiponectin 脂连蛋白;
BDNF 神经营养因子
bFGF碱性成纤维生长因子
BMP-7 骨形态发生蛋白-7
EGF上表皮生长因子
follistatin卵泡休止素
GMCSF粒—巨噬细胞集落刺激因子
IGF1胰岛素样生长因子1
Leptin 瘦素
PDGF-BB血小板源性生长因子-BB
Myostatin 肌肉生长抑制素
Prolactin 催乳素
RANKL细胞核因子κB受体活化因子配基
SCF 干细胞因子
TGF Beta3转化生长因子-β3
TNF Alpha 肿瘤坏死因子α
VEGF 血管内皮生长因子
白介素系列
产品详情:
Catalogue Number | CYT-152 |
Synonyms | IRAP, IL1F3, IL1RA, IL-1ra3, ICIL-1RA, IL1RN, IL1 inhibitor, IL-1ra, MGC10430. |
Introduction | Interleukin-1 ra is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Description | IL 1RA Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 17.5kDa. The IL 1RA Rat is purified by proprietary chromatographic techniques. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
Solubility | It is recommended to reconstitute the lyophilized IL 1RA in sterile 18M?-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Stability | Lyophilized IL 1RA although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL 1RA should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles. |
Purity | Greater than 95.0% as determined by SDS-PAGE. |
Amino acid sequence | HPAGKRPCKM QAFRIWDTNQ KTFYLRNNQL IAGYLQGPNT KLEEKIDMVP IDFRNVFLGI HGGKLCLSCV KSGDDTKLQL EEVNITDLNK NKEEDKRFTF IRSETGPTTS FESLACPGWF LCTTLEADHP VSLTNTPKEP CTVTKFYFQE DQ |
Biological Activity | Fully biologically active when compared to standard. Measured by its ability to inhibit IL1a-dependent proliferation in D10.G4.1 mouse helper T cells. The ED50 for this effect is typically 30-150ng/ml (corresponding to a specific activity of 6,667-33,334units/mg ) in the presence of 50pg/ml of rrIL1a. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Related Products | ? 重组马白介素1拮抗剂/IL 1RA Horse ? 重组人白介素1拮抗剂/IL 1RA Human ? 重组人白介素1拮抗剂/IL 1RA Human His ? 重组小鼠白介素1拮抗剂/IL 1RA Mouse ? 重组小鼠白介素1拮抗剂/IL 1RA Mouse, His ? 重组猪白介素1拮抗剂/IL 1RA Porcine ? 重组人白介素-1受体样1/IL1RL1 Human |
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