重组大鼠脑多巴胺神经营养因子|Rat CDNF|5ug|CYT-730-上海高创化学科技有限公司

产品详情

ProSpec（蛋白质专家）是以色列一家具有超过16年历史的，专业从事细菌来源重组蛋白生产的先进生物技术公司。ProSpec生产多种细胞因子、生长因子、趋化因子、激素、酶、病毒抗原和许多其他重组蛋白。在研究团队和科学家们的努力下，ProSpec已经拥有超过1700种可用于癌症、细胞凋亡、发育、内分泌学、免疫学、神经科学、蛋白酶及干细胞研究用重组蛋白、多肽和抗体。10多年蛋白纯化方面的经验使ProSpec公司生产成本低、产量高、效率高，其蛋白产品不仅纯度高、生物活性高，价格也非常具有优势。同时ProSpec针对客户的需要提供自定义重组蛋白生产服务。

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产品详情：

Catalogue Number	CYT-730
Synonyms	Cerebral dopamine neurotrophic factor, ARMET-like protein 1, Arginine-rich protein mutated in early stage tumors-like 1, Conserved dopamine neurotrophic factor, Cdnf, Armetl1.
Introduction	CDNF is a member of the ARMET family and acts as a trophic factor for dopamine neurons. CDNF inhibits the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When CDNF controlled after 6-OHDA-lesioning, it reestablishes the dopaminergic function and inhibits the degeneration of dopaminergic neurons in substantia nigra. CDNF is universally expressed in neuronal and non-neuronal tissues. The highest levels in the brain are found in the optic nerve and corpus callosum.
Description	CDNF Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 163 amino acids and having a molecular mass of 18.8kDa. The CDNF is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	CDNF protein was lyophilized from a 0.2μm filtered concentrated solution in 1xPBS, pH 7.4.
Solubility	It is recommended to reconstitute the lyophilized CDNF in sterile 18M-cm H₂O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized CDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CDNF should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity	Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino acid sequence	QGLEAGVRSR ADCEVCKEFL NRFYNSLLTR GIDFSVDTIE EELISFCADT KGKENRLCYY LGATKDSATK ILGEVTRPMS VHMPTVKICE KLKKMDSQIC ELKYEKKLDL ESVDLWKMRV AELKQILHSW GEECRACAEK HDYVNLIKEL APKYVETRPQ TEL.
Biological Activity	CDNF Rat is able to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons when immobilized at 5-25 μg/mL on a nitrocellulose-coated microplate.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products	? 重组人脑多巴胺神经营养因子/CDNF Human ? 重组小鼠脑多巴胺神经营养因子/CDNF Mouse

供货周期：	一周
品牌：	Prospec-Tany
规格：	5ug
货号：	CYT-730
CAS号：