供货周期: | 7天 |
品牌: | |
型号: | 2μg |
货号: | CYT-577 |
Recombinant Human Vascular Endothelial Growth Factor, Yeast人血管内皮生长因子
Synonyms | Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, VEGF, MGC70609. |
Introduction |
Vascular endothelial growth factor is an important signaling protein involved in both vasculogenesis and angiogenesis. As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces angiogenesis, vasculogenesis and endothelial cell growth, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. |
Description | Vascular Endothelial Growth Factor Human Recombinant produced in Yeast is a double, glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 42 kDa. |
Source | Pichia Pastoris. |
Physical Appearance | Sterile Filtered colorless liquid formulation. |
Formulation | The protein contains 20mM Phosphate- Buffered Saline, pH 7.4. |
Stability |
Vascular Endothelial Growth Factor Human although stable at 15°C for 2 weeks, should be stored below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Purity | Greater than 90.0% as determined by SDS-PAGE. |
Biological Activity | Determined by its ability to stimulate 3H-Thymidine incorporation in human umbilical vein endothelial cells, the ED50 for this effect was found to be 2-6ng/ml. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
Related Products |
相关产品
猴糜蛋白酶样弹性蛋白酶1(ELA1)ELISA kit
猴弹性蛋白酶2,中性粒细胞(ELA2)ELISA kit
牛脂多糖/内毒素(LPS) ELISA kit
大鼠细胞色素P450 2B1(Cyp2b1)ELISA kit
Dog Cytochrome P450 2B11(Cyp2b11) ELISA kit
Mouse Methylthioadenosine Phosphorylase(MTAP)ELISA kit
豚鼠胰淀粉酶α2A(AMY2A)ELISA Kit
猪胰岛素样生长因子1(IGF-1)ELISA Kit
人Klotho ELISA Kit
小鼠Klotho ELISA Kit
小鼠嗅觉标记蛋白(OMP)ELISA kit
人运甲状腺素蛋白/前白蛋白(TTR)ELISA kit
Human Placenta-specific gene 8 protein(PLAC8) ELISA kit
小鼠L氨基酸氧化酶(IL4I1)ELISA kit
植物过氧化氢酶2(CAT2/CAT)ELISA kit
详细地址
关注
拨打电话
留言咨询