Mouse Anti MHC Class II (I-A) FITC|500 μg|ANT-270-上海顺元生物科技有限公司

产品详情

Type

Mouse Antibody Monoclonal.

Introduction

MHC Class II is consists of 2 membrane spanning proteins. Each of these proteins is roughly 30 kDa, and has of two Globular domains, Alpha-1, Alpha-2, Beta-1 and Beta-2. The two regions farthest away from the membrane are alpha-1 and beta-1. The two proteins link without Covalent Bonds. The MHC Class II protein mainly presents peptides, which have been digested from external sources. MHC Class II is normally only expressed by Antigen Presenting Cells (APC) which digest foreign protein. Within the RER the alpha and beta proteins of the molecule, associate with each other, while a third protein called the "invariant chain," is necessary for stabilizing the complex, without it, they will not associate. The MHC-invariant complex is then passed from the RER, into and out of, the Golgi body. It fuses with an Endocytic compartment, where an external protein has been sampled and degraded.

Clone

NYRmI-A.

Immunogen

Purified mouse LN B cells (C3H anti-C57Bl6).

Ig Subclass

Mouse IgG2a.

Specificity

Recognizes most MHC class II haplotypes (b,f,p,q,r,s,u,v), but weak against I-Ak.

Purification Method

Ion exchange column.

Protein concentration

1mg/ml in PBS (after reconstitution).

Storage Procedures

Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Reconstitution

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Antibody Properties

Cytotoxic and staining antibody. For staining, use 10ml/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator.

Available Conjugates

This antibody is also available unconjugated and conjugated to Biotin.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Mouse Anti MHC Class II (I-A) FITC由上海顺元生物科技有限公司为您提供，货号ANT-270，规格：500 μg，CAS号：，如您想了解更多关于Mouse Anti MHC Class II (I-A) FITC价格、Mouse Anti MHC Class II (I-A) FITC结构式、批发、用途等信息，欢迎咨询。除供应Mouse Anti MHC Class II (I-A) FITC外，还可为您提供其他等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，顺元生物客户服务电话，售前、售后均可联系。

供货周期：	7天
品牌：
型号：	500 μg
货号：	ANT-270