丝氨酸蛋白酶抑制剂B10抗体资料说明

丝氨酸蛋白酶抑制剂B10抗体 

别名：Bomapin; PI10; Protease inhibitor 10; Protease inhibitor 10 (ovalbumin type bomapin); Serpin B10; Serpin peptidase inhibitor clade B (ovalbumin) member 10; SPB10_HUMAN. 

浓度：1mg/1ml 

规格：0.2ml/200μg   

抗体来源：Rabbit  

克隆类型：polyclonal 

交叉反应：Human  

产品类型：一抗    

研究领域：心血管 细胞生物  

蛋白分子量：predicted molecular weight: 45kDa 

性状：Lyophilized or Liquid 

免疫原：KLH conjugated synthetic peptide derived from human SERPINB10 

亚型：IgG 

纯化方法：affinity purified by Protein A 

储存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用：WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍：SERPINB10 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in human bone marrow in a search for serpins similar to SerpinB6. SERPINB10 was identified in lymphocytes, and was elevated in chronic myeloid leukemia and chronic myelomonocytic leukemia cells. The monocytic cell lines THP-1 and AML-193 also showed elevated SERPINB10 expression.

Function : Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. 

Subcellular Location : Nucleus. Cytoplasm. 

Tissue Specificity : Expressed specifically in the bone marrow.

Similarity : Belongs to the serpin family. Ov-serpin subfamily. 

Database links : UniProtKB/Swiss-Prot: P48595.1