供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.1ml/100μg 0.2ml/200μg |
货号: | |
CAS号: |
英文名称 Anti-ENPP2
中文名称 核苷酸焦磷酸酶2抗体
核苷酸焦磷酸酶2抗体别 名 ATX; ATX X; Autotaxin; Autotaxin t; E NPP 2; E-NPP 2; Ectonucleotide pyrophosphatase/phosphodiesterase 2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Enpp2; ENPP2_HUMAN; Extracellular lysophospholipase D; LysoPLD; NPP2; PD IALPHA; PDNP2; Phosphodiesterase I alpha; Phosphodiesterase I/nucleotide pyrophosphatase 2; Plasma lysophospholipase D.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、核苷酸焦磷酸酶2抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 肿瘤 心血管 细胞生物 神经生物学 生长因子和激素
蛋白分子量 predicted molecular weight: 95kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ENPP2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Function : Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell 核苷酸焦磷酸酶2抗体motility-stimulating factor.
Subcellular Location : Secreted. Note=Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells.
Tissue Specificity : Predominantly expressed in brain, placenta, ovary, and small intestine. Expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. Expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. Not detected in leukocytes. Isoform 1 is more highly Eexpressed in peripheral tissues than in the central nervous system (CNS). Adipocytes only express isoform 1. Isoform 3 is more highly expressed in the brain than in peripheral tissues.
Post-translational modifications : N-glycosylation, but not furin-cleavage, plays a critical role on secretion and on lysoPLD activity (By similarity).
It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.
Similarity : Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
Contains 2 SMB (somatomedin-B) domains.
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Human CKMB ELISA Kit 人激动异构酶MB(CKMB)
Human SDF-1—Stromal cell derived factor 1 ELISA kit 人基质衍生因子-1B(SDF-1β) ELISA kit
Human Tissue inhibitor of matrix metalloproteinase-4,TIMP-4 ELISA kit 人基质金属蛋白酶抑制因子4(TIMP-4)
Human Tissue inhibitor of matrix metalloproteinase-3,TIMP-3 ELISA kit 人基质金属蛋白酶抑制因子3(TIMP-3)
Human Tissue inhibitor of matrix metalloproteinase-2,TIMP-2 ELISA kit 人基质金属蛋白酶抑制因子2(TIMP-2)
Human TIMP-1 ELISA Kit 人基质金属蛋白酶抑制因子-1(TIMP-1)
Human Tissue inhibitor of matrix metalloproteinase-1,TIMP-1 ELISA kit 人基质金属蛋白酶抑制因子1(TIMP-1)
Human MMP-9 ELISA Kit 人基质金属蛋白酶-9(MMP-9) ELISA试剂盒
Human Matrix metalloproteinase-8—MMP-8 ELISA kit 人基质金属蛋白酶8(MMP-8)
Human Matrix metalloproteinase-7—MMP-7 ELISA kit 人基质金属蛋白酶7(MMP-7)
Human MMP-5 ELISA Kit 人基质金属蛋白酶5(MMP-5)
Human MMP-4 ELISA Kit 人基质金属蛋白酶4(MMP-4)
Human Matrix metalloproteinase-3—MMP-3 ELISA kit 人基质金属蛋白酶3(MMP-3)ELISA kit
Human Matrix metalloproteinase-2—MMP-2 ELISA kit 人基质金属蛋白酶2(MMP-2)
Human Matrix metalloproteinase-13—MMP-13 ELISA kit 人基质金属蛋白酶13(MMP-13)
Human Matrix metalloproteinase-10—MMP-10 ELISA kit 人基质金属蛋白酶10(MMP-10)
Human MMP-1——Matrix metalloproteinase-1 ELISA kit 人基质金属蛋白酶1(MMP-1)
Human Myosin ELISA Kit 人肌球蛋白(Myosin)
Human Myoglobin ELISA Kit 人肌红蛋白(MYO)ELISA Kit
Human Tn-T ELISA Kit 人肌钙蛋白-T(Tn-T)
Human Troponin I ELISA Kit 人肌钙蛋白-I(Tn-I)ELISA Kit
Human Activin A ELISA Kit 人活化素A(Activin A)
Human Acti-vated protein C ELISA Kit 人活化蛋白C
Human cAMP Elisa Kit 人环-磷酸腺苷(cAMP)
Human Cyclic guanosine monophosphate ELISA Kit 人环-磷鸟苷(cGMP)
Human Cyclosporin A ELISA Kit 人环胞霉素A(CSA)ELISA Kit
核苷酸焦磷酸酶2抗体Human Erythropoietin soluble receptor ELISA Kit 人红细胞生成素受体(EPO sR)
Human Erythropoietin ELISA Kit 人红细胞生成素(EPO)ELISA Kit
Human Actinin α ELISA Kit 人横纹肌辅肌动蛋白α (Actinin α ) ELISA试剂盒
Human anti-melanocyte ELISA Kit 人黑色素细胞抗体(melanocyte)ELISA试剂盒
更多核苷酸焦磷酸酶2抗体价格、 核苷酸焦磷酸酶2抗体批发价、 核苷酸焦磷酸酶2抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取。
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