烯醇化酶超家族成员1抗体

参考价:¥1
供货周期: 现货
品牌: GenWay
规格: 0.1ml/100μg 0.2ml/200μg
货号:
CAS号:
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英文名称  Anti-ENOSF1 

中文名称  烯醇化酶超家族成员1抗体 

烯醇化酶超家族成员1抗体别    名  Enolase superfamily member 1; ENOSF 1; HSRTSBETA; RTS alpha; RTS; RTS beta; RTS beta protein; TYMSAS;  

浓    度  1mg/1ml 

规 格  0.2ml/200μg     

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Dog, Rabbit

产品类型  一抗    

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研究领域  肿瘤 细胞生物 信号转导 新陈代谢  

蛋白分子量  predicted molecular weight: 50kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human ENOSF1 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

烯醇化酶超家族成员1抗体保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The rTS gene codes for a naturally occurring antisense RNA to thymidylate synthase (TS) mRNA and two proteins (rTSalpha and rTSbeta (also known as ENOSF1)). The role of the major protein product of rTS, ENOSF1 has been linked to alterations in TS protein expression, but the precise function of ENOSF1 is unknown. Expression of rTS is associated with growth arrest in cell culture, but its overexpression has been noted in cells resistant to anticancer drugs such as 5-fluorouracil and methotrexate. Studies have shown that increased expression of ENOSF1 is associated with the decrease in TS protein expression due to production of novel, diffusible signal molecules.

Function : May regulate thymidylate synthase activity. 

Subcellular Location : Mitochondrial.

Post-translational modifications : Could be sumoylated. 

Similarity : Belongs to the mandelate racemase/muconate lactonizing enzyme family. ENOSF1 subfamily. 

Database links : UniProtKB/Swiss-Prot: Q7L5Y1.1

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