EB病毒核抗原-3A抗体|0.1ml/100μg 0.2ml/200μg |-上海研生实业有限公司

产品详情

英文名称 Anti-EBNA 3A

中文名称 EB病毒核抗原-3A抗体

EB病毒核抗原-3A抗体别名 nuclear antigen EBNA-3; Epstein-Barr nuclear antigen 3; EBV nuclear antigen 3; EBNA-3; Epstein-Barr nuclear antigen 3A; EBV nuclear antigen 3A; EBNA-3A; Epstein Barr Virus; EBV-NA3; EBNA3_EBVG.

浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 EBV/HHV4

产品类型一抗

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研究领域转录调节因子

蛋白分子量 predicted molecular weight: 103kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from EBV (Human herpesvirus 4) EBNA 3A (321-345aa)

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

EB病毒核抗原-3A抗体产品介绍 EBNA3A is a latent viral nuclear protein expressed in Epstein Barr Virus (EBV) transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA3A functions as a transcriptional regulator though the target genes are currently unknown.

Function : Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.

Subunit : Interacts with human UCKL1. Interacts with host CTPB1; this interaction seems important for EBNA3-mediated transcriptional repression. Interacts with host RBPJ.

Subcellular Location : Host nucleus matrix. Note=Associated with the nuclear matrix.

Similarity : Belongs to the herpesviridae EBNA-3 family.

Database links : UniProtKB/Swiss-Prot: Q3KST2.2

EB病毒核抗原-3（nuclear antigen EBNA-3）是EB病毒编码核蛋白，位于细胞核的新的酶聚合体，主要作为转录调节因子，指导蛋白与蛋白之间相互作用，为核糖核苷酸补救途径的一部分.

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2

EB病毒核抗原-3A抗体ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2

ANG-2 (Rabbit Angiopoietin 2) ELISA Kit 兔血管生成素2

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供货周期：	现货
品牌：	GenWay
规格：	0.1ml/100μg 0.2ml/200μg
货号：
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