供货周期: | 现货 |
品牌: | GenWay |
规格: | 0.2ml/200μg |
货号: | |
CAS号: |
英文名称 Anti-SIRT6
中文名称 沉默调节相关蛋白6抗体
沉默调节相关蛋白6抗体别 名 2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2L6; SIRT 6; SIRT6; SIR6_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae); Sirtuin 6; Sirtuin type 6; Sirtuin6.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat
产品类型 一抗
公司全程供应Abcam、CST、Abnova、BD、GeneTex、Proteintech、SB、Abgent、AbFrontier、AnaSpec、Agrisera、Alomone、Epitomics、Active Motif、Assaybiotech、Biorbyt、BioVision、Bender、CaymanChemical、Covance、ChromoTek、Enzo、eBioscience、Glen Research、MBL、ProSci、PeproTech、Swant、Vector等品牌公司抗体,产品货期短、沉默调节相关蛋白6抗体品质保证、全国免邮,并提供抗体相应实验技术指导。
研究领域 肿瘤 心血管 免疫学 染色质和核信号 信号转导 细胞凋亡 新陈代谢 表观遗传学
蛋白分子量 predicted molecular weight: 39kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SIRT6
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
沉默调节相关蛋白6抗体产品介绍 NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein.
Function : NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
Anti-Integrin beta 7 整合素β7抗体 Multi-class antibodies 规格: 0.1ml
Anti-Integrin Alpha V + Beta1 整合素αVβ1抗体 Multi-class antibodies 规格: 0.2ml
Anti-Integrin Alpha V + Beta 3 整合素αVβ3抗体 Multi-class antibodies 规格: 0.2ml
沉默调节相关蛋白6抗体Anti-Integrin Alpha V + Beta 5 整合素αVβ5抗体 Multi-class antibodies 规格: 0.2ml
Anti-Integrin alpha E/CD103 整合素αE抗体 Multi-class antibodies 规格: 0.2ml
Anti-IQGAP1 支架蛋白抗体 Multi-class antibodies 规格: 0.2ml
Anti-IRF-1 干扰素调节因子1抗体 Multi-class antibodies 规格: 0.2ml
Anti-IRAK 白介素-1受体相关激酶1/2抗体 Multi-class antibodies 规格: 0.2ml
Anti-Phospho-IRAK1 (Ser376) 磷酸化白介素-1受体相关激酶1抗体 Multi-class antibodies 规格: 0.1ml
更多沉默调节相关蛋白6抗体价格、沉默调节相关蛋白6抗体批发价、沉默调节相关蛋白6抗体品牌、厂家及抗体详细说明书,都可跟我们销售人员索取.
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