供货周期: | 一周 |
品牌: | |
规格: | 0.1ml/0.2ml |
货号: | 有货供应 |
CAS号: |
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Anti-ATXN10|脊髓小脑共济失调10抗体产品介绍:Spinocerebellar ataxia (SCA) is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss. SCA is caused by the expansion of a translated CAG repeat, encoding a polyglutamine tract in SCA gene products, known as ataxins. The ataxin proteins are ubiquitously expressed in nervous tissue, but are primarily detected in cerebellum, brain stem and spinal cord in the central nervous system. Ataxin-10 is a cytoplasmic protein that belongs to the family of armadillo repeat proteins. A loss of ataxin-10 in primary neuronal cells causes increased apoptosis of cerebellar neurons. Ataxin-10 interacts with p110, an O-Linked beta-N-acetylglucosamine transferase, and may be important in the regulation of intracellular glycosylation levels and homeostasis in the brain. Spinocerebellar ataxia type 10 (SCA10) is an autosomal dominant disorder that causes cerebellar ataxia and seizures. SCA10 is caused by an expansion of an ATTCT pentanucleotide repeat in intron 9 of the ataxin-10 gene.
【产品名称】:Anti-ATXN10|脊髓小脑共济失调10抗体
【产品编号】:BYK-11806R
【规 格】:0.1ml/0.2ml
【相关标记】:Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647 AP APC Biotin Cy3 Cy5 Cy5.5 Cy7 FITC Gold HRP PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 RBITC
【产品别名】:Mycoplasma Gallisepticum.
【浓 度】:1mg/1ml
【抗体来源】:Rabbit or Mouse or Goat
【克隆类型】:polyclonal or monoclonal
【产品类型】:一抗
【性 状】:Lyophilized or Liquid
【亚 型】:IgG
【纯化方法】:affinity purified by Protein A
【储 存 液】:0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
【产品应用】:not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
【保存条件】:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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