AQP8抗体/说明书sc-28624

2014-03-21 10:16  下载量:1

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AQP8抗体/说明书sc-28624Human AQP8 (aquaporin 8) is a 261 amino acid protein that contains 6 membrane- spanning domains, 2 conserved asn-pro-ala (NPA) motifs, which are characteristic of MIP (major intrinsic protein) family members, and 3 N-linked glycosylation sites. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption

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