细胞衰老抑制基因蛋白抗体

本公司是最专业细胞衰老抑制基因蛋白抗体供应商，提供细胞衰老抑制基因蛋白抗体的报价，泛素样蛋白Sumo2/3抗体咨询，

英文名称  Anti-RSL1D1

中文名称  细胞衰老抑制基因蛋白抗体

别    名  CATX 11; CATX-11; CATX11; Cellular senescence inhibited gene protein; Cellular senescence-inhibited gene protein; CSIG; L12; PBK1; Protein PBK1; Ribosomal L1 domain containing 1; Ribosomal L1 domain-containing protein 1; RL1D1_HUMAN; RSL1D1.

浓    度  1mg/1ml

规 格  0.2ml/200μg

细胞衰老抑制基因蛋白抗体概述：

B淋巴细胞在抗原的刺激下，能够分化、增殖形成具有针对这种抗原分泌特异性抗体的能力。B细胞的这种能力和量是有限的，不可能持续分化增殖下去，因此产生免疫球蛋白的能力也是极其微小的。将这种B细胞与非分泌型的骨髓瘤细胞融合形成杂交瘤细胞，再进一步克隆化，这种克隆化的杂交瘤细胞是既具有瘤细胞的无限分裂的能力，又具有产生特异性抗体的B淋巴细胞的能力。将这种克隆化的杂交瘤细胞进行培养或注入小鼠腹水内即可获得大量的高效、单一的特异性抗体。这种技术即称为单克隆抗体技术。

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Cow, Sheep

产品类型  一抗    

研究领域  肿瘤 细胞生物 信号转导 细胞周期蛋白 细胞分化 表观遗传学  

蛋白分子量  predicted molecular weight: 55kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human RSL1D1

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 RSL1D1, also known as CATX-11, PBK1, L12 or CSIG, is a 490 amino acid nuclear protein that belongs to the ribosomal protein L1P family. Expressed in placenta, RSL1D1 contains many phosphorylated amino acid residues and is encoded by a gene that maps to human chromosome 16p13.13. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias.

Subcellular Location : Nucleus

Tissue Specificity : Placenta

Similarity : Belongs to the ribosomal protein L1P family. Highly divergent.

Database links :

细胞衰老抑制基因蛋白抗体Entrez Gene: 26156 Human

SwissProt: O76021 Human

Unigene: 401842 Human