胰岛细胞再生因子β抗体

我公司专业供应胰岛细胞再生因子β抗体。了解更多关于的胰岛细胞再生因子β抗体英文名称胰岛细胞再生因子β抗体产品别名规格请看以下说明书。

英文名称  Anti-REG1β/REG1 beta

中文名称  胰岛细胞再生因子β抗体

别    名  Lithostathine 1 beta; Lithostathine 1 beta precursor; PSPS2; Regenerating islet derived 1 beta (pancreatic stone protein pancreatic thread protein); Regenerating islet derived 1 beta; Regenerating protein I beta; REGH; REGI BETA; REGL; Secretory pancreatic stone protein 2; REG1B_HUMAN.

浓    度  1mg/1ml

规 格  0.2ml/200μg

胰岛细胞再生因子β抗体的功能：

抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat

产品类型  一抗    

研究领域  细胞生物 免疫学  

蛋白分子量  predicted molecular weight: 16kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human REG1β/REG1 beta

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

Function : Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

Subcellular Location : Secreted.

胰岛细胞再生因子β抗体Post-translational modifications : All O-linked glycans consist of Gal-GlcNAc-Gal-GalNAc tetrasaccharide core and get elongated (microheterogeneity).

Similarity : Contains 1 C-type lectin domain.

Database links : UniProtKB/Swiss-Prot: P48304.1