视网膜感光细胞外节膜蛋白1抗体

我公司专业供应视网膜感光细胞外节膜蛋白1抗体。了解更多关于的视网膜感光细胞外节膜蛋白1抗体英文名称视网膜感光细胞外节膜蛋白1抗体产品别名规格请看以下说明书。

英文名称  Anti-ROM1

中文名称  视网膜感光细胞外节膜蛋白1抗体

别    名  Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23.

浓    度  1mg/1ml

规 格  0.2ml/200μg

视网膜感光细胞外节膜蛋白1抗体的功能：

抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。                                                                       

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat

产品类型  一抗    

研究领域  神经生物学 细胞粘附分子 细胞膜蛋白  

蛋白分子量  predicted molecular weight: 37kDa

性    状  Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human ROM1

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008].

Function : May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

视网膜感光细胞外节膜蛋白1抗体DISEASE : Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2.

Similarity : Belongs to the PRPH2/ROM1 family.

Database links : UniProtKB/Swiss-Prot: Q03395.2