蛋白酶体PSMβ6抗体

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英文名称  Anti-Proteasome 20S beta 6

中文名称  蛋白酶体PSMβ6抗体

别    名  Delta; LMPY; Macropain delta chain; MGC5169; Multicatalytic endopeptidase complex delta chain; Proteasome (prosome macropain) subunit beta type 6; Proteasome beta 6 subunit; Proteasome catalytic subunit 1; Proteasome delta chain; Proteasome subunit beta 6; Proteasome subunit beta type 6; Proteasome subunit beta type-6; Proteasome subunit delta; Proteasome subunit Y; PSB6_HUMAN; PSMB 6; PSMB6; PSY large multifunctional protease Y; Y antibody.

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit  

克隆类型  polyclonal

交叉反应  Human, Mouse, Rat, Pig

产品类型  一抗    

研究领域  细胞生物 免疫学 细胞周期蛋白 细胞分化  

蛋白分子量  predicted molecular weight: 22kDa

性    状  Lyophilized or Liquid

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免 疫 原  KLH conjugated synthetic peptide derived from human Proteasome 20S beta 6

亚    型  IgG

纯化方法  affinity purified by Protein A

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-F=1:100-500  IF=1:50-200

（石蜡切片需做抗原修复）

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Function : The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Subunit : The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. This subunit can be displaced by the equivalent immune-specific subunit PSMB9. Interacts with -1 TAT protein.

蛋白酶体PSMβ6抗体Subcellular Location : Cytoplasm. Nucleus.

Similarity : Belongs to the peptidase T1B family.

Database links : UniProtKB/Swiss-Prot: P28072.4